Attenuated Airway Eosinophilic Inflammations in IL-38 Knockout Mouse Model
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چکیده
منابع مشابه
P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma.
Leukotriene E4 (LTE4) that plays a key role in airway inflammation is expressed on platelets and eosinophils. We investigated whether blocking of the P2Y12 receptor can suppress eosinophilic inflammation in a mouse model of asthma because platelets and eosinophils share this receptor to be activated. BALB/c mice were sensitized by intraperitoneal injection of ovalbumin (OVA), followed by OVA ne...
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ژورنال
عنوان ژورنال: The Kurume Medical Journal
سال: 2018
ISSN: 0023-5679,1881-2090
DOI: 10.2739/kurumemedj.ms652009